SCHEMBL195548

SCHEMBL195548

Nc1nc2c(nc(O)n2[C@H]2CC(O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PNP P00491 3/20 0.55
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
ADRB1 P08588 1/20 0.45
DNMT1 P26358 1/20 0.45
POLB P06746 1/20 0.44
LMNA P02545 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TK1 P04183 1/20 0.42
TP53 P04637 1/20 0.41
HTT P42858 1/20 0.41
PDE4D Q08499 1/20 0.41
PDE3A Q14432 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
ALOX12 P18054 1/20 0.40
ADRA1A P35348 1/20 0.40
TLR7 Q9NYK1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21779018 1.00 PNP (0.55) PNPCYP3A4MAPTADRB1DNMT1
SCHEMBL114652 1.00 PNP (0.55) PNPCYP3A4MAPTADRB1DNMT1
Phosphoric Acid SCHEMBL9013988 0.96 PNP (0.52) PNPCYP3A4MAPTADRB1DNMT1
SCHEMBL655857 0.90 PNP (0.65) PNPCYP3A4MAPTADRB1DNMT1
SCHEMBL655858 0.90 PNP (0.65) PNPCYP3A4MAPTADRB1DNMT1
Citric Acid SCHEMBL3066161 0.89 PNP (0.46) PNPCYP3A4MAPTADRB1DNMT1
SCHEMBL3868526 0.88 PNP (0.54) PNPCYP3A4MAPTADRB1DNMT1
SCHEMBL13351290 0.88 PNP (0.54) PNPCYP3A4MAPTADRB1DNMT1
SCHEMBL18723297 0.88 PNP (0.54) PNPCYP3A4MAPTADRB1DNMT1
SCHEMBL14543297 0.88 PNP (0.54) PNPCYP3A4MAPTADRB1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634399-A1 MAMMALIAN SPERMATOZOA DNA INTEGRITY TESTING VIA EVALUATION OF ITS 8-OXODG CONTENT Université Clermont Auvergne (FR) 2025-10-22 EP claimed
US-20250288555-A1 SYSTEMS AND METHODS TO IMPROVE EXERCISE TOLERANCE EPICENTRX, INC. (US) 2025-09-18 US claimed
US-12359000-B2 Anti-8-hydroxy-2′-deoxyguanosine antibody or antibody fragment thereof, production method, kit, measuring method, and device for measurement TDK CORPORATION (JP) 2025-07-15 US claimed
US-12352695-B2 System and method for monitoring the health of dialysis patients VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2025-07-08 US claimed
EP-4553065-A2 NOVEL COMPOUNDS FOR TREATING MITOCHONDRIAL DISEASE KHONDRION IP B.V. (NL) 2025-05-14 EP claimed
EP-4551234-A1 REDOX-MODULATING ORGANELLE COMPLEXES LUCA Science Inc. (JP) 2025-05-14 EP claimed
WO-2025076473-A1 PROTEINS BISPECIFIC TO CD3 AND NKG2DL AND ASSOCIATED USES THEREOF FRED HUTCHINSON CANCER CENTER (US) 2025-04-10 WO claimed
WO-2024254556-A9 BACTERIAL COMPOSITIONS FOR METABOLIZING UREMIC TOXINS ATOSSA THERAPEUTICS, INC. (US) 2025-01-30 WO claimed
WO-2024254556-A1 BACTERIAL COMPOSITIONS FOR METABOLIZING UREMIC TOXINS ATOSSA THERAPEUTICS, INC. (US) 2024-12-12 WO claimed
US-20240280590-A1 COMPOSITIONS AND METHODS FOR FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY BIOMARKER DETECTION UNIVERSITY OF WASHINGTON (US) 2024-08-22 US claimed
US-20060281809-A1 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers PTC THERAPEUTICS, INC. 2006-12-14 US claimed
WO-2006130775-A2 REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMAKERS EDISON PHARMACEUTICALS, INC. (US) 2006-12-07 WO claimed
US-20060105384-A1 Detection of DNA damage DIONEX CORPORATION 2006-05-18 US claimed
US-20060099634-A1 Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor ECOLOGICAL TECHNOLOGY RESEARCH, LTD. (JP) 2006-05-11 US claimed
US-20050112572-A1 Detecting oxidation stresses in sampling using markers; measurement; calibration PROBIOX SA (BE) 2005-05-26 US claimed
EP-1423518-A2 PROCESS FOR THE DETECTION OF OXIDATIVE STRESS AND KIT FOR ITS IMPLEMENTATION Probiox SA (BE) 2004-06-02 EP claimed
US-20030186260-A1 Simple method of biologically evaluating natural and artificial chemicals by using dna injury index and apparatus therefor ECOLOGICAL TECHNOLOGY RESEARCH, LTD. (JP) 2003-10-02 US claimed
US-6548252-B1 Electrochemically analyzing samples from selected areas of the body of a living organism for elevated free levels of nucleotide excision products resulting from DNA or RNA damage ESA, INC. 2003-04-15 US claimed
WO-2003016527-A2 PROCESS FOR THE DETECTION OF OXIDATIVE STRESS AND KIT FOR ITS IMPLEMENTATION PROBIOX SA (BE) 2003-02-27 WO claimed
EP-1267162-A1 SIMPLE METHOD OF BIOLOGICALLY EVALUATING NATURAL AND ARTIFICIAL CHEMICALS BY USING DNA INJURY INDEX AND APPARATUS THEREFOR Ecological Technology Research, Ltd. (JP) 2002-12-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288555-A1 SYSTEMS AND METHODS TO IMPROVE EXERCISE TOLERANCE SPR, GYS1, PYGM PNP 857/4885CYP3A4 889/4885MAPT 4863/4885
US-20060281809-A1 Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers ECHS1, FH, ACAA2 PNP 3872/4885CYP3A4 4235/4885MAPT 1658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.