Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.48 |
| ▸ | CTSB | P07858 | 5/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559234 | 0.92 | CTSK (0.50) | CTSKCTSBPSMB1RENCTSD | |
| SCHEMBL6559868 | 0.85 | PSMB1 (0.39) | PSMB1RENCTSD | |
| SCHEMBL6558995 | 0.85 | PSMB1 (0.56) | CTSKCTSBPSMB1CTSSCTSL | |
| SCHEMBL6560838 | 0.83 | CTSK (0.52) | CTSKCTSBPSMB1RENCTSS | |
| SCHEMBL6558612 | 0.79 | PSMB1 (0.50) | CTSKCTSBPSMB1RENCTSS | |
| SCHEMBL6564394 | 0.79 | PSMB1 (0.50) | CTSKCTSBPSMB1CTSSCTSL | |
| SCHEMBL6560880 | 0.79 | PSMB1 (0.64) | CTSKCTSBPSMB1CTSSCTSL | |
| SCHEMBL6558606 | 0.78 | PSMB1 (0.43) | CTSKPSMB1RENCTSDCTSS | |
| SCHEMBL7741834 | 0.78 | CASP3 (0.40) | CTSDCASP3CASP7CASP1 | |
| SCHEMBL6559358 | 0.77 | CTSD (0.45) | CTSDCASP3CASP7CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |