Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6560628 | 0.82 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL946385 | 0.71 | SLC6A2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4017281 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL8162225 | 0.66 | — | — | |
| SCHEMBL21867278 | 0.64 | HTR2A (0.38) | — | |
| Hydrochloric Acid SCHEMBL3170692 | 0.61 | HTR2A (0.34) | — | |
| SCHEMBL21250760 | 0.60 | SLC6A2 (0.33) | — | |
| Methane SCHEMBL8935403 | 0.60 | HTR2A (0.33) | — | |
| Hydrochloric Acid SCHEMBL6909498 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL7208697 | 0.57 | ADRA2C (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683016-B1 | SLURRYING METALLOCENE AND ACTIVATOR, APPLYING SONIC WAVES OR VIBRATION WAVES, WASHING WITH HYDROCARBON SOLVENT, DRYING; EVEN PENETRATION INTO PORE SPACE OF SUPPORT | DAELIM INDUSTRIAL CO., LTD. (KR) | 2004-01-27 | — | — | US | disclosed |
| EP-1042375-B1 | SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH | DAELIM IND CO LTD (KR) | 2004-01-02 | — | — | EP | disclosed |
| EP-1042375-A1 | SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH | DAELIM INDUSTRIAL CO., LTD. (KR) | 2000-10-11 | — | — | EP | disclosed |
| WO-2000023483-A1 | SUPPORTED METALLOCENE CATALYST, ITS PREPARATION METHOD AND OLEFIN POLYMERIZATION THEREWITH | DAELIM INDUSTRIAL CO., LTD. (KR) | 2000-04-27 | — | — | WO | disclosed |
| US-5866662-A | HAS AT ONE OR BOTH ENDS AN OLEFINICALLY UNSATURATED GROUP HAVING AT LEAST 3 CARBON ATOMS. | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |