Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3170692 | 0.98 | HTR2A (0.34) | HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL2483036 | 0.85 | SLC6A2 (0.36) | HTR2A | |
| Hydrochloric Acid SCHEMBL7129103 | 0.81 | SLC6A2 (0.32) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL6557429 | 0.80 | KDM1A (0.34) | — | |
| Methane SCHEMBL8163328 | 0.79 | HTR2A (0.33) | HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL9412837 | 0.79 | NR3C1 (0.39) | HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL6559838 | 0.79 | ALDH1A1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7938541 | 0.77 | HTR2A (0.34) | HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL8905301 | 0.76 | HTR2A (0.33) | HTR2ACYP19A1 | |
| Methane SCHEMBL8935426 | 0.76 | GPR3 (0.31) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480948-A | WITH CATALYST OF /A/ORGANOALUMINOXY PRODUCT FORMED BY REACTING ORGANOALUMINOXANE AND ORGANIC PEROXIDE, ALKYLENE OXIDE OR ORGANIC CARBONATE AND /B/GROUP IVB OR VB METAL HYDROCARBYL, CYCLOPENTADIENYL, ALKOXIDE, ARYLOXIDE, HALIDE OR HYDRIDE | PHILLIPS PETROLEUM COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0677526-A1 | Organoaluminoxy product, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5436212-A | Coordination polymerization catalysts for olefins | PHILLIPS PETROLEUM COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| US-5416179-A | Metallocene, isobutene | PHILLIPS PETROLEUM COMPANY (US) | 1995-05-16 | — | — | US | disclosed |