Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 9/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 4/20 | 0.37 |
| ▸ | METAP1 | P53582 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7359588 | 0.81 | METAP2 (0.39) | CPB2RENMETAP2METAP1CTSS | |
| SCHEMBL6486232 | 0.81 | METAP2 (0.39) | CPB2RENMETAP2METAP1CTSS | |
| SCHEMBL7351879 | 0.81 | LTA4H (0.47) | CPB2RENMETAP2METAP1CTSS | |
| SCHEMBL7327231 | 0.78 | REN (0.39) | RENMETAP2METAP1CTSSCTSK | |
| SCHEMBL27822264 | 0.75 | METAP2 (0.38) | CPB2RENMETAP2METAP1CTSS | |
| SCHEMBL7350002 | 0.70 | METAP2 (0.48) | CPB2RENMETAP2METAP1 | |
| SCHEMBL10767496 | 0.69 | REN (0.42) | RENMETAP2METAP1CTSSCTSK | |
| SCHEMBL5709586 | 0.66 | REN (0.44) | RENMETAP2METAP1CTSK | |
| SCHEMBL5709584 | 0.66 | REN (0.41) | RENMETAP2METAP1CTSK | |
| SCHEMBL6565088 | 0.65 | METAP2 (0.56) | CPB2RENMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |