Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561051 | 0.81 | CA2 (0.38) | SLC6A2SLC6A4SLC6A3KDM4EMAPK1 | |
| SCHEMBL6562323 | 0.74 | CTSD (0.35) | LMNAALDH1A1 | |
| SCHEMBL6561042 | 0.69 | CA2 (0.39) | KDM4EMAPK1POLBLMNACA2 | |
| SCHEMBL28596915 | 0.65 | GAA (0.41) | POLBALDH1A1TSHRMAPT | |
| SCHEMBL2053058 | 0.64 | CYP26A1 (0.46) | LMNACA2ALDH1A1HSD17B10HTT | |
| SCHEMBL10592034 | 0.63 | TLR3 (0.36) | SLC6A2SLC6A4SLC6A3KDM4EMAPK1 | |
| SCHEMBL10339554 | 0.63 | HSD11B1 (0.48) | KDM4EHSD11B1HSD11B2 | |
| SCHEMBL31326461 | 0.63 | HSD11B1 (0.48) | KDM4EHSD11B1HSD11B2 | |
| SCHEMBL5569860 | 0.61 | CA2 (0.43) | SLC6A2SLC6A4SLC6A3KDM4EMAPK1 | |
| SCHEMBL27554946 | 0.61 | PGR (0.38) | KDM4EPOLBSLC22A12ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1085009-B1 | INDAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6486178-B1 | Indane derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| EP-1085009-A1 | INDAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |