Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.41 |
| ▸ | F10 | P00742 | 8/20 | 0.41 |
| ▸ | PLAU | P00749 | 6/20 | 0.41 |
| ▸ | PLAT | P00750 | 6/20 | 0.41 |
| ▸ | PLG | P00747 | 5/20 | 0.41 |
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 4/20 | 0.41 |
| ▸ | F3 | P13726 | 3/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563737 | 0.90 | EGLN1 (0.45) | EGLN1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7675063 | 0.89 | F2 (0.48) | F2F10PLAUPLATPLG | |
| SCHEMBL6563625 | 0.87 | PRSS1 (0.43) | F2F10F7F3ASIC3 | |
| SCHEMBL6563213 | 0.87 | KMT2A (0.39) | F2PLAUPLGPRSS1EGLN1 | |
| SCHEMBL6565256 | 0.84 | AKR1C3 (0.44) | F2F10PLAUPLATPLG | |
| SCHEMBL6563680 | 0.84 | PPARG (0.40) | PLAUKLK1KLK5ASIC3PRSS1 | |
| SCHEMBL7675036 | 0.83 | F10 (0.42) | F2F10PLAUPLATPLG | |
| SCHEMBL6563588 | 0.82 | F2 (0.41) | F2F10PLAUPLATPLG | |
| SCHEMBL6565349 | 0.82 | F2 (0.38) | F2F10PLAUPLATPLG | |
| SCHEMBL7677481 | 0.81 | F2 (0.47) | F2F10PLAUPLATPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |