Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563737 | 0.92 | EGLN1 (0.45) | KMT2AMEN1RAB9AEGLN1GRM5 | |
| SCHEMBL6563651 | 0.88 | MAPK13 (0.45) | KMT2APRSS1MEN1NPC1RAB9A | |
| SCHEMBL6563532 | 0.87 | ALDH1A1 (0.44) | KMT2AF2PLGPLAUKLKB1 | |
| SCHEMBL6563277 | 0.87 | F2 (0.41) | F2PLGPLAUPRSS1EGLN1 | |
| SCHEMBL6564223 | 0.83 | VNN1 (0.41) | KMT2AF2PLGPLAUKLKB1 | |
| SCHEMBL6565231 | 0.83 | GAA (0.41) | KMT2AMRGPRX4POLBMAPT | |
| SCHEMBL6562060 | 0.80 | PLA2G7 (0.39) | EGLN1VNN1GRM5LRRK2 | |
| SCHEMBL6565408 | 0.80 | CNR1 (0.41) | KMT2AMEN1NPC1RAB9AVNN1 | |
| SCHEMBL6565480 | 0.79 | GSK3B (0.47) | VNN1SRD5A2 | |
| SCHEMBL7808322 | 0.79 | NPC1 (0.39) | KMT2ANPC1RAB9AEGLN1VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |