Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | F7 | P08709 | 4/20 | 0.42 |
| ▸ | F3 | P13726 | 4/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.41 |
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | PLAT | P00750 | 3/20 | 0.41 |
| ▸ | PLG | P00747 | 3/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563625 | 0.89 | PRSS1 (0.43) | F7F3F2F10PRSS1 | |
| SCHEMBL6563946 | 0.89 | KLK1 (0.42) | F2F10PLAUPLATPLG | |
| SCHEMBL7675063 | 0.89 | F2 (0.48) | F2F10PLAUPLATPLG | |
| SCHEMBL7677481 | 0.88 | F2 (0.47) | F7F3F2F10PLAU | |
| SCHEMBL6563277 | 0.84 | F2 (0.41) | F7F3F2F10PLAU | |
| SCHEMBL6561827 | 0.82 | MRGPRX1 (0.51) | F7F3F2F10PLG | |
| SCHEMBL7670899 | 0.82 | PRSS1 (0.43) | F2F10PLAUPLATPLG | |
| SCHEMBL7674188 | 0.81 | EGLN1 (0.44) | F2F10PLAUPLATPLG | |
| SCHEMBL7677130 | 0.80 | PRSS1 (0.41) | F2KLK1KLK5PRSS1PRSS2 | |
| SCHEMBL7670696 | 0.80 | KMT2A (0.44) | F2F10PLATPLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |