Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563213 | 0.92 | KMT2A (0.39) | EGLN1SRD5A2GRM5MAPK13MAPK12 | |
| SCHEMBL6563277 | 0.90 | F2 (0.41) | EGLN1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6565231 | 0.79 | GAA (0.41) | KDM4EHPGDGAAKMT2ALMNA | |
| SCHEMBL6563651 | 0.79 | MAPK13 (0.45) | EGLN1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL6563680 | 0.78 | PPARG (0.40) | KDM4EL3MBTL1HPGDGAALMNA | |
| SCHEMBL6565427 | 0.78 | VNN1 (0.46) | EGLN1GRM5L3MBTL1RAB9AKCNK3 | |
| SCHEMBL7675063 | 0.77 | F2 (0.48) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL29712728 | 0.76 | SMN1; SMN2 (0.50) | EGLN1GRM5TDP1ALDH1A1HPGD | |
| SCHEMBL6563325 | 0.76 | KMT2A (0.50) | EGLN1GRM5TDP1MAPK13MAPK12 | |
| SCHEMBL6563532 | 0.76 | ALDH1A1 (0.44) | EGLN1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |