Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.48 |
| ▸ | PLAU | P00749 | 4/20 | 0.48 |
| ▸ | PLAT | P00750 | 4/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | KLK1 | P06870 | 3/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563277 | 0.89 | F2 (0.41) | F2PLAUPLATF10KLK1 | |
| SCHEMBL6565256 | 0.89 | AKR1C3 (0.44) | F2PLAUPLATF10KLK1 | |
| SCHEMBL7677481 | 0.88 | F2 (0.47) | F2PLAUPLATF10KLK1 | |
| SCHEMBL6563625 | 0.87 | PRSS1 (0.43) | F2F10MAPK13MAPK12MAPK11 | |
| SCHEMBL6563946 | 0.87 | KLK1 (0.42) | F2PLAUPLATF10KLK1 | |
| SCHEMBL6563651 | 0.86 | MAPK13 (0.45) | MAPK13MAPK12MAPK11MAPK14PRSS1 | |
| SCHEMBL7670899 | 0.84 | PRSS1 (0.43) | F2PLAUPLATF10PLG | |
| SCHEMBL7674188 | 0.81 | EGLN1 (0.44) | F2PLAUPLATF10KLK1 | |
| SCHEMBL6563461 | 0.80 | PRSS1 (0.49) | F2PLAUPLATF10KLK1 | |
| SCHEMBL7677130 | 0.80 | PRSS1 (0.41) | F2KLK1KLK5PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |