Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565231 | 0.86 | GAA (0.41) | PPARGGAATP53MAPTSMN1; SMN2 | |
| SCHEMBL6563277 | 0.84 | F2 (0.41) | PRSS1ASIC3PLAUKLK1KLK5 | |
| SCHEMBL6563737 | 0.78 | EGLN1 (0.45) | GAALMNAKDM4EL3MBTL1HPGD | |
| SCHEMBL7675063 | 0.73 | F2 (0.48) | PRSS1PLAUKLK1KLK5 | |
| SCHEMBL6563213 | 0.73 | KMT2A (0.39) | MAPTPRSS1PLAU | |
| SCHEMBL5885884 | 0.72 | PTPN1 (0.39) | L3MBTL1PRSS1ASIC3PLAU | |
| SCHEMBL6563625 | 0.71 | PRSS1 (0.43) | LMNAL3MBTL1PRSS1ASIC3HPGD | |
| Hydrochloric Acid SCHEMBL5885907 | 0.71 | PTPN1 (0.39) | L3MBTL1PRSS1ASIC3PLAU | |
| SCHEMBL5885889 | 0.70 | F10 (0.38) | PRSS1ASIC3 | |
| SCHEMBL6563946 | 0.69 | KLK1 (0.42) | SMN1; SMN2PRSS1HPGDPLAUKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |