Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.37 |
| ▸ | F10 | P00742 | 11/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562325 | 0.91 | PRSS1 (0.36) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6563242 | 0.87 | EGLN1 (0.39) | — | |
| SCHEMBL6563607 | 0.86 | ITGB3 (0.40) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6565338 | 0.85 | F2 (0.36) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6565355 | 0.82 | F2 (0.42) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6562064 | 0.80 | ADAM17 (0.43) | F2F10 | |
| SCHEMBL6565346 | 0.80 | ITGB3 (0.39) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6561873 | 0.77 | ITGB3 (0.38) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6565274 | 0.77 | ITGB3 (0.39) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6563233 | 0.77 | TMPRSS15 (0.38) | F2PRSS1PRSS2PRSS3ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |