Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 8/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563233 | 0.91 | TMPRSS15 (0.38) | F2PRSS1PRSS2PRSS3ITGB3 | |
| SCHEMBL6565355 | 0.88 | F2 (0.42) | F2PRSS1PRSS2PRSS3NQO2 | |
| SCHEMBL6563579 | 0.85 | F2 (0.37) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6562064 | 0.81 | ADAM17 (0.43) | F2F10LTA4H | |
| SCHEMBL6563619 | 0.79 | F2 (0.41) | F2PRSS1PRSS2PRSS3NQO2 | |
| SCHEMBL6562325 | 0.78 | PRSS1 (0.36) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL6561682 | 0.73 | NQO2 (0.39) | F2PRSS1NQO2F10ITGB3 | |
| SCHEMBL6563285 | 0.72 | ITGB3 (0.39) | F2PRSS1NQO2F10ITGB3 | |
| SCHEMBL6562044 | 0.72 | NQO2 (0.37) | F2PRSS1NQO2F10ITGB3 | |
| SCHEMBL6563711 | 0.72 | ADAM17 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |