Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.42 |
| ▸ | F10 | P00742 | 8/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563619 | 0.92 | F2 (0.41) | F2F10ITGB3ITGA2BNQO2 | |
| SCHEMBL6565338 | 0.88 | F2 (0.36) | F2F10ITGB3ITGA2BNQO2 | |
| SCHEMBL6562064 | 0.85 | ADAM17 (0.43) | F2F10LTA4H | |
| SCHEMBL6563579 | 0.82 | F2 (0.37) | F2F10ITGB3ITGA2BPRSS1 | |
| SCHEMBL6563152 | 0.80 | F2 (0.43) | F2F10NQO2PRSS1PRSS2 | |
| SCHEMBL6563233 | 0.80 | TMPRSS15 (0.38) | F2ITGB3ITGA2BPRSS1PRSS2 | |
| SCHEMBL6562325 | 0.77 | PRSS1 (0.36) | F2F10ITGB3ITGA2BPRSS1 | |
| SCHEMBL6563711 | 0.76 | ADAM17 (0.47) | — | |
| SCHEMBL6565497 | 0.75 | PLAU (0.48) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6563644 | 0.73 | F2 (0.45) | F2F10ITGB3ITGA2BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |