Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 4/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676492 | 0.88 | CCNA2 (0.41) | GALR3RAB9ATDP1NAMPTVNN1 | |
| SCHEMBL6563325 | 0.87 | KMT2A (0.50) | GALR3RAB9ATDP1EGLN1PLOD2 | |
| SCHEMBL6563676 | 0.80 | NAMPT (0.42) | GALR3RAB9ATDP1NAMPTALDH1A1 | |
| SCHEMBL6563532 | 0.80 | ALDH1A1 (0.44) | RAB9AEGLN1VNN1ALDH1A1L3MBTL1 | |
| SCHEMBL6564996 | 0.79 | KMT2A (0.54) | RAB9AEGLN1ALDH1A1L3MBTL1KCNK3 | |
| SCHEMBL29712676 | 0.79 | CHRNB2 (0.66) | EGLN1CYP2A6CYP2C9CHRNB2CYP2B6 | |
| SCHEMBL6565427 | 0.78 | VNN1 (0.46) | RAB9AEGLN1VNN1L3MBTL1KCNK3 | |
| SCHEMBL6563625 | 0.78 | PRSS1 (0.43) | RAB9AALDH1A1L3MBTL1LMNA | |
| SCHEMBL29712728 | 0.77 | SMN1; SMN2 (0.50) | RAB9ATDP1EGLN1ALDH1A1LMNA | |
| SCHEMBL6563737 | 0.75 | EGLN1 (0.45) | RAB9ATDP1EGLN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |