Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565417 | 0.91 | PTPN11 (0.36) | HRH3GAAHPGDPTPN11NAMPT | |
| SCHEMBL6563511 | 0.90 | PTPN11 (0.40) | PTPN11NPC1HSD11B1 | |
| SCHEMBL6563920 | 0.89 | KLK5 (0.41) | PTPN11ALDH1A1NPC1 | |
| SCHEMBL6561835 | 0.88 | PTPN11 (0.35) | HRH3GAAHPGDPTPN11NAMPT | |
| SCHEMBL6563605 | 0.88 | GAA (0.37) | HRH3GAAHPGDNAMPTALDH1A1 | |
| SCHEMBL6563591 | 0.86 | LRRK2 (0.39) | HRH3GAAHPGDNAMPTALDH1A1 | |
| SCHEMBL6561858 | 0.86 | GRM5 (0.47) | HRH3HPGDPTPN11NAMPTALDH1A1 | |
| SCHEMBL7686729 | 0.86 | PTPN11 (0.43) | HPGDPTPN11NAMPTALDH1A1LMNA | |
| SCHEMBL7674981 | 0.86 | ABL1 (0.43) | GAAHPGDPTPN11NAMPTALDH1A1 | |
| SCHEMBL6563752 | 0.85 | GAA (0.35) | HRH3GAAHPGDNAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |