Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561875 | 0.89 | HPGD (0.47) | HPGDSHPGDRAB9ANPC1TSHR | |
| SCHEMBL7670097 | 0.87 | HPGD (0.45) | HPGDSHPGDRAB9ANPC1TSHR | |
| SCHEMBL6563325 | 0.81 | KMT2A (0.50) | HPGDRAB9ACYP2C9LMNAALDH1A1 | |
| SCHEMBL29712728 | 0.78 | SMN1; SMN2 (0.50) | HPGDRAB9ANPC1LMNAALDH1A1 | |
| SCHEMBL28782860 | 0.76 | CA1 (0.56) | HPGDRAB9ANPC1TSHRCYP2C9 | |
| SCHEMBL6563532 | 0.75 | ALDH1A1 (0.44) | HPGDRAB9ANPC1LMNAALDH1A1 | |
| SCHEMBL6564996 | 0.75 | KMT2A (0.54) | HPGDRAB9ANPC1LMNAALDH1A1 | |
| SCHEMBL6563589 | 0.74 | GALR3 (0.50) | RAB9ACYP2C9LMNAALDH1A1EGLN1 | |
| SCHEMBL6565427 | 0.74 | VNN1 (0.46) | RAB9ANPC1EGLN1MEN1KMT2A | |
| SCHEMBL11133426 | 0.74 | PTPN11 (0.47) | RAB9ANPC1TSHRCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |