Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565403 | 0.87 | HPGDS (0.54) | HPGDNPC1RAB9ATSHRHTT | |
| SCHEMBL6561875 | 0.86 | HPGD (0.47) | HPGDNPC1RAB9ATSHRHTT | |
| SCHEMBL6563625 | 0.83 | PRSS1 (0.43) | HPGDRAB9AALDH1A1LMNAPRSS1 | |
| SCHEMBL7677130 | 0.81 | PRSS1 (0.41) | MEN1KMT2APRSS1F2PRSS2 | |
| SCHEMBL7670899 | 0.81 | PRSS1 (0.43) | ALDH1A1LMNAPRSS1F2PRSS2 | |
| SCHEMBL7674188 | 0.80 | EGLN1 (0.44) | LMNAPRSS1F2PRSS2PRSS3 | |
| SCHEMBL7675063 | 0.79 | F2 (0.48) | ALDH1A1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6565256 | 0.79 | AKR1C3 (0.44) | ALDH1A1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7677481 | 0.78 | F2 (0.47) | KMT2AALDH1A1POLBPRSS1F2 | |
| SCHEMBL6563946 | 0.77 | KLK1 (0.42) | HPGDNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |