Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563589 | 0.87 | GALR3 (0.50) | EGLN1PLOD2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7677130 | 0.85 | PRSS1 (0.41) | KMT2AMEN1NPSR1 | |
| SCHEMBL6564996 | 0.83 | KMT2A (0.54) | KMT2AMEN1EGLN1NPSR1HTT | |
| SCHEMBL29712728 | 0.81 | SMN1; SMN2 (0.50) | KMT2AMEN1EGLN1HTTALDH1A1 | |
| SCHEMBL6563532 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1EGLN1NPSR1HTT | |
| SCHEMBL6565403 | 0.81 | HPGDS (0.54) | KMT2AMEN1EGLN1HTTALDH1A1 | |
| SCHEMBL6565427 | 0.80 | VNN1 (0.46) | KMT2AMEN1EGLN1GRM5KCNK3 | |
| SCHEMBL6563625 | 0.79 | PRSS1 (0.43) | ALDH1A1HPGDLMNAMAPK13MAPK12 | |
| SCHEMBL28782860 | 0.79 | CA1 (0.56) | KMT2AMEN1EGLN1ALDH1A1CYP1A2 | |
| SCHEMBL11133426 | 0.77 | PTPN11 (0.47) | KMT2AMEN1EGLN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |