Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL6566367

CCOc1ccc2cccc([S+]3CCCC3)c2c1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 9/20 0.41
GAA P10253 2/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 4/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
KAT6A Q92794 1/20 0.34
MTNR1B P49286 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TYMS P04818 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TTK P33981 1/20 0.32
MAPK8 P45983 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL6566222 0.92 MTNR1A (0.35) MTNR1AGAAMAPK1TDP1L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL6563576 0.92 MTNR1A (0.42) MTNR1AKAT6AMTNR1B
Trifluoromethanesulfonic Acid SCHEMBL6564004 0.91 GAA (0.39) MTNR1AGAAMAPK1TDP1L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL6562415 0.91 MTNR1A (0.35) MTNR1AMTNR1B
Trifluoromethanesulfonic Acid SCHEMBL6564570 0.89 MTNR1A (0.38) MTNR1AMTNR1B
Trifluoromethanesulfonic Acid SCHEMBL6566068 0.88 MTNR1A (0.42) MTNR1AMTNR1B
Trifluoromethanesulfonic Acid SCHEMBL7796611 0.86 ALOX5 (0.43) MTNR1AGAATDP1SMN1; SMN2
Trifluoromethanesulfonic Acid SCHEMBL6566193 0.86 KMT2A (0.37) MTNR1AGAAKDM4EALDH1A1HPGD
Trifluoromethanesulfonic Acid SCHEMBL6565959 0.83 GAA (0.34) GAAMAPK1TDP1L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL6562385 0.83 MTNR1A (0.36) MTNR1AMAPK1KDM4ETSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849634-B1 Radiation sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6322949-B2 SULFONIUM COMPOUND AS PHOTOACID GENERATOR JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-27 US disclosed
US-20010014427-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-08-16 US disclosed
US-6187504-B1 PHOTOSENSITIVE BLEND CONTAINING A NAPHTHALENE SULFONIUM SULFONATE DERIVATIVE PHOTOACID GENERATOR, RESIN HAVING ALKALI INSOLUBLE GROUPS CLEAVABLE BY ACID, AN ALKALI SOLUBLE RESIN AND A SOLUBILITY CONTROL AGENT; POSITIVES, RESOLUTION JSR CORPORATION (JP) 2001-02-13 US disclosed
EP-0849634-A1 Radiation sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-06-24 EP disclosed