Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.61 |
| ▸ | ADH1C | P00326 | 1/20 | 0.61 |
| ▸ | ADH1A | P07327 | 1/20 | 0.61 |
| ▸ | ADH7 | P40394 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763196 | 0.83 | ADH1B (0.76) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL4473619 | 0.78 | LMNA (0.40) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL28421794 | 0.78 | ADH1B (0.38) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL8763263 | 0.76 | ADH1B (0.67) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL27354 | 0.76 | ADH1B (1.00) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL3112488 | 0.75 | TPSAB1 (0.44) | KMT2AMEN1 | |
| SCHEMBL8129476 | 0.75 | SIGMAR1 (0.41) | ADH1BADH1CADH1AADH7KMT2A | |
| Hydrochloric Acid SCHEMBL3741186 | 0.74 | ADH1B (0.95) | ADH1BADH1CADH1AADH7KMT2A | |
| SCHEMBL4633427 | 0.74 | ADH1B (0.52) | ADH1BADH1CADH1AADH7ALOX5 | |
| SCHEMBL4633463 | 0.73 | ADH1B (0.61) | ADH1BADH1CADH1AADH7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | MERCK PATENT GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1377543-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002083630-A1 | OXALIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-10-24 | — | — | WO | disclosed |
| CN-1050376-A | Acyl-CoA: cholesterol acyltransferase inhibitor | WARBER LAMBERT CO (US) | 1991-04-03 | — | — | CN | disclosed |
| US-4837305-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0117089-B1 | BETA-ADRENERGIC ANTAGONIST COMPOUNDS AND DERIVATIVES OF BETA-ADRENERGIC ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-12-14 | — | — | EP | disclosed |
| US-4687873-A | Derivatives of β-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0117089-A1 | Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220411-A1 | Oxalic acid derivatives | F11, F2, F12 | ADH1B 977/4885ADH1C 673/4885ADH1A 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.