SCHEMBL6566809

SCHEMBL6566809

CC(C)(c1ccccc1)c1cccc(OC(=O)CCC(N)C(=O)Oc2cccc(C(C)(C)c3ccccc3)c2C(C)(C)c2ccccc2)c1C(C)(C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 15/20 0.34
LTA4H P09960 3/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
RECQL P46063 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6566814 0.93 RBP4 (0.35) KIF11LTA4H
SCHEMBL6566813 0.92 KIF11 (0.43) KIF11LTA4H
SCHEMBL1681408 0.84 KDM4E (0.45) KDM4EMEN1RECQLKMT2A
SCHEMBL1681409 0.81 MEN1 (0.42) KDM4EMEN1RECQLKMT2A
SCHEMBL27488778 0.80 TDP1 (0.37) KIF11KDM4EMEN1RECQLKMT2A
SCHEMBL29601094 0.77 TDP1 (0.40) KDM4EMEN1KMT2A
SCHEMBL247099 0.77 TDP1 (0.40) KDM4EMEN1KMT2A
SCHEMBL247100 0.77 TDP1 (0.40) KDM4EMEN1KMT2A
SCHEMBL10631084 0.75 SMN1; SMN2 (0.32) KDM4E
SCHEMBL1870707 0.73 ATM (0.37) KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780409-B1 Low fogging rubbery polymer ELIOKEM SAS (FR) 2004-03-31 EP disclosed
EP-0780409-A2 Low fogging rubbery polymer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-06-25 EP disclosed