Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574537 | 1.00 | ALDH1A1 (0.45) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL28145232 | 0.98 | ALDH1A1 (0.47) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL10951765 | 0.98 | ALDH1A1 (0.47) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL28661870 | 0.89 | EPHX2 (0.55) | PPARGPPARDPPARAPTPN1TDP1 | |
| SCHEMBL1305332 | 0.84 | DNM1 (0.49) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL10698778 | 0.83 | DGKA (0.52) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL21064713 | 0.82 | CES2 (0.46) | ALDH1A1CES2CES1DNM1ESR1 | |
| SCHEMBL9066139 | 0.81 | DNM1 (0.50) | ALDH1A1CES2CES1DNM1GPR84 | |
| SCHEMBL28174057 | 0.81 | CES2 (0.46) | ALDH1A1CES2CES1GPR84PPARG | |
| SCHEMBL3963400 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CES2CES1DNM1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040091438-A1 | Polyorganosiloxane emulsions,process for producing the same and material for cosmetic preparation | DOW CORNING TORAY SILICONE CO. LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1394215-A1 | POLYORGANOSILOXANE EMULSION, PROCESS FOR PRODUCING THE SAME, AND MATERIAL FOR COSMETIC PREPARATION | Dow Corning Toray Silicone Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040091438-A1 | Polyorganosiloxane emulsions,process for producing the same and material for cosmetic preparation | CUTA, UNG, PCNA | ALDH1A1 720/4885CES2 3015/4885CES1 2217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.