Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431234 | 0.90 | KMT2A (0.42) | TRPA1AMY1ATDP1TP53IDO1 | |
| SCHEMBL18723288 | 0.86 | KDM4E (0.41) | TDP1TP53MAPTKMT2AALDH1A1 | |
| SCHEMBL17886767 | 0.85 | ALDH1A1 (0.42) | TDP1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL17808642 | 0.85 | PTGS1 (0.44) | TRPA1TDP1TP53MAPTKMT2A | |
| SCHEMBL16014627 | 0.84 | ACHE (0.48) | TRPA1AMY1ATDP1TP53IDO1 | |
| SCHEMBL6567310 | 0.81 | TRPA1 (0.54) | TRPA1AMY1ATDP1TP53IDO1 | |
| SCHEMBL17886969 | 0.80 | GAA (0.41) | TDP1TP53MAPTKMT2AALDH1A1 | |
| SCHEMBL17886873 | 0.79 | LMNA (0.37) | TRPA1TP53MAPTKMT2AALDH1A1 | |
| SCHEMBL18826296 | 0.77 | TRPA1 (0.56) | TRPA1AMY1ATDP1TP53IDO1 | |
| SCHEMBL19820287 | 0.77 | ESR2 (0.46) | MAPTKMT2AALDH1A1MEN1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670239-B2 | Bisphosphites having an outer naphthyl-phenyl unit and a central 2,3′-biphenol unit | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9670108-B2 | Bisphosphites having a central 2,3′-biphenol unit | EVONIK DEGUSSA GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| US-9643987-B2 | Monophosphites having an unsymmetric biaryl unit | EVONIK DEGUSSA GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9617290-B2 | Bisphosphites having an outer naphthyl-phenyl unit | EVONIK DEGUSSA GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20160159835-A1 | BISPHOSPHITES HAVING AN OUTER NAPHTHYL-PHENYL UNIT | EVONIK DEGUSSA GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159836-A1 | BISPHOSPHITES HAVING AN OUTER NAPHTHYL-PHENYL UNIT AND A CENTRAL 2,3'-BIPHENOL UNIT | EVONIK DEGUSSA GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159838-A1 | MONOPHOSPHITES HAVING AN UNSYMMETRIC BIARYL UNIT | EVONIK DEGUSSA GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160159839-A1 | BISPHOSPHITES HAVING AN UNSYMMETRIC CENTRAL BIARYL UNIT | EVONIK DEGUSSA GMBH (DE) | 2016-06-09 | — | — | US | disclosed |
| US-20160010225-A1 | ELECTROCHEMICAL COUPLING OF TWO PHENOLS WHICH DIFFER IN THEIR OXIDATION POTENTIAL | EVONIK DEGUSSA GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159839-A1 | BISPHOSPHITES HAVING AN UNSYMMETRIC CENTRAL BIARYL UNIT | BPGM, BCR, PTH1R | TRPA1 4484/4885AMY1A 4828/4885TDP1 4523/4885 |
| US-20160010225-A1 | ELECTROCHEMICAL COUPLING OF TWO PHENOLS WHICH DIFFER IN THEIR OXIDATION POTENTIAL | COMT, MT-CO2, CYP11B2 | TRPA1 2870/4885AMY1A 4442/4885TDP1 3961/4885 |
| US-20160159835-A1 | BISPHOSPHITES HAVING AN OUTER NAPHTHYL-PHENYL UNIT | BPGM, SOST, PPA1 | TRPA1 2707/4885AMY1A 4746/4885TDP1 3953/4885 |
| US-20160159836-A1 | BISPHOSPHITES HAVING AN OUTER NAPHTHYL-PHENYL UNIT AND A CENTRAL 2,3'-BIPHENOL UNIT | BPGM, PHOSPHO1, PPA1 | TRPA1 4016/4885AMY1A 4781/4885TDP1 4191/4885 |
| US-20160159838-A1 | MONOPHOSPHITES HAVING AN UNSYMMETRIC BIARYL UNIT | RUVBL2, RFC4, HIRIP3 | TRPA1 4370/4885AMY1A 2978/4885TDP1 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.