Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 6/20 | 0.41 |
| ▸ | CTSB | P07858 | 6/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565429 | 0.87 | CTSL (0.40) | UTS2RCTSLCTSBCTSKCTSS | |
| SCHEMBL6567349 | 0.87 | CTSS (0.47) | UTS2RCTSLCTSBCTSKCTSS | |
| SCHEMBL3902637 | 0.85 | CTSL (0.48) | UTS2RCTSLCTSBCTSKCTSS | |
| SCHEMBL6565444 | 0.81 | CTSL (0.42) | UTS2RCTSLCTSBCTSKCTSS | |
| SCHEMBL3902634 | 0.78 | CTSS (0.49) | CTSLCTSBCTSKCTSS | |
| SCHEMBL6565455 | 0.77 | CTSS (0.45) | UTS2RCTSLCTSBCTSKCTSS | |
| SCHEMBL3906527 | 0.77 | CTSL (0.45) | CTSLCTSBCTSKCTSSCASP3 | |
| SCHEMBL3893070 | 0.75 | CTSS (0.43) | UTS2RCTSLCTSBCTSKCTSS | |
| SCHEMBL3893067 | 0.75 | CTSK (0.43) | UTS2RCTSLCTSBCTSKCTSS | |
| SCHEMBL6565039 | 0.74 | CTSS (0.46) | UTS2RCTSLCTSBCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100849-A2 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |