Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570105 | 0.86 | SIGMAR1 (0.61) | MAOBSIGMAR1HRH3NPC1RAB9A | |
| SCHEMBL6569763 | 0.83 | HRH3 (0.54) | MAOBSIGMAR1HRH3 | |
| SCHEMBL17828185 | 0.76 | HRH3 (0.75) | SIGMAR1HRH3ACHEL3MBTL1 | |
| SCHEMBL156202 | 0.74 | HRH3 (0.76) | SIGMAR1HRH3RAB9AACHE | |
| SCHEMBL491791 | 0.74 | HRH3 (0.72) | SIGMAR1HRH3 | |
| SCHEMBL24429026 | 0.69 | KDM4E (0.40) | HRH3ACHE | |
| SCHEMBL5426586 | 0.69 | MCHR1 (0.74) | HRH3RAB9AACHE | |
| SCHEMBL6570156 | 0.68 | SIGMAR1 (0.43) | MAOBSIGMAR1HRH3NPC1RAB9A | |
| SCHEMBL20232771 | 0.68 | HRH3 (0.61) | SIGMAR1HRH3ACHE | |
| SCHEMBL8821505 | 0.65 | SPHK1 (0.60) | MAOBSIGMAR1HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |