Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570100 | 0.87 | SIGMAR1 (0.51) | SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6569758 | 0.84 | HRH3 (0.45) | SIGMAR1NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL6570120 | 0.73 | L3MBTL1 (0.47) | SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6052744 | 0.72 | SIGMAR1 (0.44) | SIGMAR1NPC1RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL6570161 | 0.68 | MAOB (0.48) | SIGMAR1NPC1RAB9ASMN1; SMN2MAOB | |
| SCHEMBL17828185 | 0.68 | HRH3 (0.75) | SIGMAR1HRH3 | |
| SCHEMBL6570152 | 0.68 | SIGMAR1 (0.43) | SIGMAR1NPC1RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL491791 | 0.67 | HRH3 (0.72) | SIGMAR1HRH3 | |
| SCHEMBL156202 | 0.66 | HRH3 (0.76) | SIGMAR1RAB9AHRH3 | |
| SCHEMBL19705213 | 0.64 | TEAD1 (0.39) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |