Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466844 | 0.89 | MEN1 (0.51) | SMN1; SMN2HPGDALDH1A1TAAR1RIPK1 | |
| SCHEMBL15720861 | 0.88 | MAPT (0.48) | SMN1; SMN2HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL27305404 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDALDH1A1TAAR1RIPK1 | |
| SCHEMBL1304013 | 0.86 | — | — | |
| SCHEMBL29955953 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDALDH1A1TAAR1RIPK1 | |
| SCHEMBL7417217 | 0.84 | TRPM8 (0.47) | SMN1; SMN2HPGDALDH1A1TAAR1RIPK1 | |
| Hydrochloric Acid SCHEMBL28582399 | 0.84 | HPGD (0.53) | SMN1; SMN2HPGDALDH1A1TAAR1RIPK1 | |
| SCHEMBL13696513 | 0.82 | TAAR1 (0.46) | SMN1; SMN2HPGDALDH1A1TAAR1RIPK1 | |
| SCHEMBL3323517 | 0.82 | MAOA (0.54) | SMN1; SMN2HPGDALDH1A1LMNATSHR | |
| SCHEMBL13051292 | 0.82 | TSHR (0.50) | SMN1; SMN2HPGDALDH1A1RIPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867202-B1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2017-08-09 | — | — | EP | disclosed |
| US-9187442-B2 | Method for producing stereoselective epoxyketone compound | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150126755-A1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2867202-A2 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-9018403-B2 | Method for producing tetrahydropyran compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20140256921-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-11 | — | — | US | disclosed |
| US-8765974-B2 | Method for producing tetrahydropyran compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| EP-2420504-B1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2014-01-15 | — | — | EP | disclosed |
| WO-2014003203-A2 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-01-03 | — | — | WO | disclosed |
| US-20120046476-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| EP-2420504-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2012-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256921-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | CYP3A5, CYP2E1, CYP3A43 | SMN1; SMN2 3176/4885HPGD 44/4885ALDH1A1 235/4885 |
| US-20150126755-A1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | HSD17B7, CYP51A1, AKR1B10 | SMN1; SMN2 3996/4885HPGD 512/4885ALDH1A1 331/4885 |
| US-20120046476-A1 | METHOD FOR PRODUCING TETRAHYDROPYRAN COMPOUND AND INTERMEDIATE THEREOF | HPD, CYP3A5, CYP2E1 | SMN1; SMN2 3324/4885HPGD 63/4885ALDH1A1 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.