Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.43 |
| ▸ | RARG | P13631 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570731 | 0.90 | HDAC2 (0.38) | PTGER4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6574651 | 0.89 | LMNA (0.43) | RARBRARGEGFRF2PRSS1 | |
| SCHEMBL6572946 | 0.87 | PTPN11 (0.42) | PTGER4F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6573438 | 0.85 | RARB (0.42) | RARBRARGF2PRSS1PRSS2 | |
| SCHEMBL6571056 | 0.84 | MGAM (0.36) | F2PRSS1PRSS2PRSS3RELA | |
| SCHEMBL6571429 | 0.84 | ALDH1A1 (0.36) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6571926 | 0.83 | F2 (0.38) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6572008 | 0.83 | MAPT (0.35) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL6570799 | 0.83 | GRM2 (0.38) | F2PRSS1PRSS2PRSS3MAP4K4 | |
| SCHEMBL6570859 | 0.83 | S100B (0.37) | F2PRSS1PRSS2PRSS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-6500213-B1 | Oxidizing hair coloring agents containing 2,5-diamino-1-phenylbenzene derivatives and novel 2,5-diamino-1-phenylbenzene derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-31 | — | — | US | disclosed |