Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572946 | 0.94 | PTPN11 (0.42) | LMNAGAAF2PRSS1PRSS2 | |
| SCHEMBL6572668 | 0.89 | RARB (0.43) | F2PRSS1PRSS2PRSS3PTPN11 | |
| SCHEMBL6574647 | 0.88 | PTGER1 (0.45) | F2PRSS1PRSS2PRSS3KMO | |
| SCHEMBL6573465 | 0.83 | KMO (0.42) | KMOPTPN11MAP4K4 | |
| SCHEMBL6570731 | 0.82 | HDAC2 (0.38) | GAAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6574642 | 0.80 | LTB4R2 (0.43) | GAAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6571056 | 0.79 | MGAM (0.36) | GAAF2PRSS1PRSS2PRSS3 | |
| SCHEMBL6571429 | 0.78 | ALDH1A1 (0.36) | F2PRSS1PRSS2PRSS3SMN1; SMN2 | |
| SCHEMBL6571441 | 0.78 | CYP3A4 (0.38) | F2PRSS1PRSS2PRSS3MAP4K4 | |
| SCHEMBL6571926 | 0.78 | F2 (0.38) | GAAF2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051143-B1 | OXIDIZING HAIR COLORING AGENTS CONTAINING 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES AND NOVEL 2,5-DIAMINO-1-PHENYLBENZENE DERIVATIVES | WELLA AG (DE) | 2004-07-21 | — | — | EP | claimed |