Sugi Predict

Sugi Predict / Compounds / SCHEMBL6573590

SCHEMBL6573590

SCHEMBL6573590

Clc1ccccc1CC1(C2(Cl)CC2)CO1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 3/20 0.38
▸ PNMT P11086 1/20 0.38
▸ CYP2A13 Q16696 2/20 0.37
▸ TAAR1 Q96RJ0 3/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ HSD11B1 P28845 1/20 0.35
▸ KCNH2 Q12809 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ SIGMAR1 Q99720 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31142998 1.00 IDO1 (0.38) IDO1PNMTCYP2A13TAAR1NPC1
SCHEMBL22371807 0.81 TAAR1 (0.36) IDO1CYP2A13TAAR1ALDH1A1MEN1
SCHEMBL8937863 0.81 IDO1 (0.37) IDO1PNMTCYP2A13TAAR1NPC1
SCHEMBL9683385 0.79 ALDH1A1 (0.40) IDO1PNMTCYP2A13TAAR1ALDH1A1
SCHEMBL22371799 0.78 KDM1A (0.35) —
SCHEMBL29290780 0.71 IDO1 (0.41) IDO1PNMTCYP2A13TAAR1NPC1
SCHEMBL9353042 0.69 KCNH2 (0.39) IDO1PNMTCYP2A13TAAR1NPC1
SCHEMBL8021114 0.69 IDO1 (0.38) IDO1PNMTCYP2A13TAAR1NPC1
SCHEMBL1824822 0.68 MAOA (0.52) IDO1PNMTTAAR1NPC1RAB9A
SCHEMBL376355 0.66 ALDH1A1 (0.42) IDO1PNMTCYP2A13NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559466-B2 Process for preparation of intermediates UPL LTD (IN) 2026-02-24 — — US claimed
EP-3762369-B1 A PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS UPL LTD (IN) 2024-12-11 — — EP claimed
CN-112204016-B Process for preparing fungicidally active triazole compounds UPL有限公司 2024-06-21 — — CN claimed
EP-4385329-A2 IMPROVED PROCESS FOR PREPARATION OF INTERMEDIATES UPL Ltd (IN) 2024-06-19 — — EP claimed
CN-117624080-A Synthesis method of prothioconazole intermediate 绍兴上虞新银邦生化有限公司 2024-03-01 — — CN claimed
CN-116102452-A Synthesis method of prothioconazole intermediate hydrazino compound 上海生农生化制品股份有限公司 2023-05-12 — — CN claimed
US-11634394-B2 Process for preparation of fungicidally active triazole compounds UPL LTD (IN) 2023-04-25 — — US claimed
US-20220089552-A1 PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS UPL LTD (IN) 2022-03-24 — — US claimed
CN-112399967-A Improved process for the preparation of intermediates UPL有限公司 2021-02-23 — — CN claimed
EP-3762369-A1 A PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS UPL Ltd (IN) 2021-01-13 — — EP claimed
WO-2019171160-A1 A PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS UPL LTD (IN) 2019-09-12 — — WO claimed
EP-1242388-B1 METHOD FOR PRODUCTION OF A TRIAZOLINETHIONE DERIVATIVE BAYER CROPSCIENCE AG (DE) 2003-07-23 — — EP claimed
US-6559317-B2 Such as 2-(1-chloro-cycloprop-1-yl)-1-(2-chloro-phenyl)-3-(4,5-dihydro-1,2,4 -triazole-5-thiono-1-yl)-propan-2-ol; microbiocides; fungicides BAYER AKTIENGESELLSCHAFT (DE) 2003-05-06 — — US claimed
US-20030013890-A1 Method for production of a triazolinethione derivative BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-01-16 — — US claimed
EP-1242388-A1 METHOD FOR PRODUCTION OF A TRIAZOLINETHIONE DERIVATIVE Bayer Aktiengesellschaft (DE) 2002-09-25 — — EP claimed
WO-2001046158-A1 METHOD FOR PRODUCTION OF A TRIAZOLINETHIONE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 2001-06-28 — — WO claimed
US-5194636-A Preparation of benzyl ketones and an oxirane BAYER AKTIENGESELLSCHAFT (DE) 1993-03-16 — — US claimed
US-5099040-A PROCESS FOR THE PREPARATION OF INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1992-03-24 — — US claimed
EP-0475122-A1 Process for the preparation of intermediates BAYER AG (DE) 1992-03-18 — — EP claimed
EP-0461483-A2 Method for the production of benzyl ketones BAYER AG (DE) 1991-12-18 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559466-B2 Process for preparation of intermediates CBR1, POR, CYP2E1 IDO1 321/4885PNMT 445/4885CYP2A13 73/4885
US-11634394-B2 Process for preparation of fungicidally active triazole compounds CAT, TYR, TH IDO1 993/4885PNMT 123/4885CYP2A13 68/4885
US-20220089552-A1 PROCESS FOR PREPARATION OF FUNGICIDALLY ACTIVE TRIAZOLE COMPOUNDS CAT, TYR, TH IDO1 993/4885PNMT 123/4885CYP2A13 68/4885
US-20030013890-A1 Method for production of a triazolinethione derivative XDH, TXN, SDHB IDO1 328/4885PNMT 3632/4885CYP2A13 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.