Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357910 | 0.98 | TYMP (0.50) | TYMPHCAR2ATAD2 | |
| SCHEMBL356483 | 0.93 | TYMP (0.49) | TYMPHCAR2ATAD2 | |
| SCHEMBL156784 | 0.85 | ATAD2 (0.48) | TYMPHCAR2ATAD2 | |
| SCHEMBL10735494 | 0.83 | KMT2A (0.50) | TYMPHCAR2GPR84 | |
| SCHEMBL7599533 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL11343851 | 0.81 | KMT2A (0.51) | TYMPHCAR2GPR84 | |
| SCHEMBL4353311 | 0.80 | DPYD (0.50) | ATAD2 | |
| SCHEMBL7603360 | 0.80 | ALDH1A1 (0.44) | — | |
| SCHEMBL7607239 | 0.80 | GAA (0.46) | — | |
| SCHEMBL161148 | 0.78 | ATAD2 (0.54) | ATAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726274-B1 | G-cap stabilized oligonucleotides | AVENTIS PHARMA GMBH (DE) | 2001-10-10 | — | — | EP | claimed |
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | claimed |
| EP-0739898-A2 | Phosphonomonoester nucleic acids, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-30 | — | — | EP | claimed |
| EP-0726274-A2 | G-cap stabilized oligonucleotides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-14 | — | — | EP | claimed |
| EP-0653439-B1 | Stabilized oligonucleotids and the use thereof | AVENTIS PHARMA GMBH (DE) | 2004-04-28 | — | — | EP | disclosed |
| EP-1182206-A2 | Stabilized oligonucleotids and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| EP-0726274-B1 | G-cap stabilized oligonucleotides | AVENTIS PHARMA GMBH (DE) | 2001-10-10 | — | — | EP | disclosed |
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-0739898-A2 | Phosphonomonoester nucleic acids, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-30 | — | — | EP | disclosed |
| EP-0726274-A2 | G-cap stabilized oligonucleotides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-14 | — | — | EP | disclosed |
| EP-0653439-A2 | Stabilized oligonucleotids and the use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |
| EP-0234494-B1 | ISOHEXIDE NUCLEOSIDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | Heinrich Mack Nachf. (DE) | 1991-03-13 | — | — | EP | disclosed |
| US-4806542-A | VIRISTATICS, IMMUNOSTIMULANTS | HEINRICH MACK NACHF. (DE) | 1989-02-21 | — | — | US | disclosed |