Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572194 | 0.87 | ACVRL1 (0.36) | NPC1MRGPRX1ALOX15KMT2A | |
| SCHEMBL6573975 | 0.85 | GAA (0.54) | NPC1RAB9AGAAMRGPRX1TSPO | |
| SCHEMBL8539307 | 0.77 | GAA (0.44) | GAAMRGPRX1ALOX15TP53 | |
| SCHEMBL8539345 | 0.74 | GAA (0.45) | GAAMRGPRX1ALOX15KMT2ATP53 | |
| SCHEMBL6575065 | 0.73 | HSD17B10 (0.37) | NPC1RAB9AGAAALOX15KMT2A | |
| SCHEMBL53468 | 0.72 | GAA (0.47) | GAAALOX15KMT2ATP53 | |
| SCHEMBL8538021 | 0.72 | GAA (0.43) | GAAALOX15TP53TYK2 | |
| SCHEMBL6812884 | 0.71 | GAA (0.47) | GAAALOX15KMT2ATP53 | |
| SCHEMBL9663368 | 0.69 | GAA (0.43) | NPC1RAB9AGAAMRGPRX1ALOX15 | |
| SCHEMBL8166988 | 0.63 | ALDH1A1 (0.37) | GAAKMT2AABL1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747365-B1 | Process and intermediates for the manufacture of herbicidal 1- [2-(cyclopropylcarbonyl)phenyl] sulfamoyl -3-(4,6-dialkoxy-2-pyrimidinyl)urea compounds | BASF AG (DE) | 2004-08-11 | — | — | EP | claimed |
| US-5847140-A | Intermediates for the manufacture of herbicidal 1-{ 2-(cyclopropylcarbonyl) Phenyl! Sulfamoyl}-3-(4,6-dialkoxy-2-pyrimidinyl) urea compounds | AMERICAN CYANAMID COMPANY (US) | 1998-12-08 | — | — | US | claimed |
| EP-0747365-A1 | Process and intermediates for the manufacture of herbicidal 1- [2-(cyclopropylcarbonyl)phenyl] sulfamoyl -3-(4,6-dialkoxy-2-pyrimidinyl)urea compounds | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | claimed |
| EP-0747365-B1 | Process and intermediates for the manufacture of herbicidal 1- [2-(cyclopropylcarbonyl)phenyl] sulfamoyl -3-(4,6-dialkoxy-2-pyrimidinyl)urea compounds | BASF AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| US-5847140-A | Intermediates for the manufacture of herbicidal 1-{ 2-(cyclopropylcarbonyl) Phenyl! Sulfamoyl}-3-(4,6-dialkoxy-2-pyrimidinyl) urea compounds | AMERICAN CYANAMID COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0747365-A1 | Process and intermediates for the manufacture of herbicidal 1- [2-(cyclopropylcarbonyl)phenyl] sulfamoyl -3-(4,6-dialkoxy-2-pyrimidinyl)urea compounds | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5559234-A | Process for the manufacture of herbicidal 1-{[2-(cyclopropylcarbonyl)phyenyl]sulfamoyl}-3-(4,6-dialkoxy-2-pyrimidinyl)urea compounds | AMERICAN CYANAMID COMPANY (US) | 1996-09-24 | — | — | US | disclosed |