Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462991 | 0.83 | ALDH1A1 (0.40) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5934756 | 0.80 | CYP3A4 (0.38) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5934568 | 0.80 | CYP3A4 (0.38) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5934301 | 0.80 | CYP3A4 (0.38) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL294716 | 0.80 | LMNA (0.43) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3691417 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL16409442 | 0.77 | LMNA (0.41) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11042018 | 0.77 | CYP1A2 (0.41) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7189787 | 0.77 | MAPT (0.39) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1577514 | 0.77 | MAPT (0.39) | MAPTALDH1A1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165560-B1 | 2-HYDROXY METHYLCYCLOPRO PYLIDENEMETHYL PURINES AS ANTIVIRAL AGENTS | UNIV MICHIGAN (US) | 2004-11-17 | — | — | EP | disclosed |