SCHEMBL6575345

SCHEMBL6575345

CCC1COC(CC2=NC(CC)CO2)=N1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.34
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877074 0.90 NOS3 (0.32) ATMNOS3NOS1NOS2
SCHEMBL27363310 0.83
SCHEMBL6762011 0.78 ATM (0.31) ATM
SCHEMBL11807514 0.77 LTA4H (0.41) ATM
SCHEMBL11807503 0.77 LTA4H (0.41) ATM
SCHEMBL10492103 0.77 ALDH1A1 (0.34) ATMNOS1NOS2
SCHEMBL10491908 0.77 ALDH1A1 (0.34) ATMNOS1NOS2
SCHEMBL10491958 0.77 ALDH1A1 (0.34) ATMNOS1NOS2
SCHEMBL10621233 0.77 ALDH1A1 (0.34) ATMNOS1NOS2
SCHEMBL10491961 0.77 ALDH1A1 (0.34) ATMNOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160185807-A1 Manganese Complexes And Use Thereof For Preparing Thin Films MERCK PATENT GMBH (DE) 2016-06-30 US disclosed
EP-0866097-B1 FLAME-RETARDANT, ANTISTATIC POLYESTER RESIN COMPOSITION KANEKA CORP (JP) 2004-01-07 EP disclosed
US-6096818-A COMPOSITION COMPRISING THERMOPLASTIC POLYESTER, BROMINE-CONTAINING FLAME RETARDANT, ANTIMONY COMPOUND, CONDUCTIVE CARBON BLACK PARTICLES KANEKA CORPORATION (JP) 2000-08-01 US disclosed
EP-0866097-A1 FLAME-RETARDANT, ANTISTATIC POLYESTER RESIN COMPOSITION KANEKA CORPORATION (JP) 1998-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160185807-A1 Manganese Complexes And Use Thereof For Preparing Thin Films SOD1, APOB, APOL1 ATM 1524/4885NOS3 377/4885NOS1 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.