Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159998 | 1.00 | ADRB2 (0.50) | ADRB2LOXL2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL6159994 | 0.99 | ADRB2 (0.49) | ADRB2LOXL2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL6575932 | 0.99 | ADRB2 (0.49) | ADRB2LOXL2HDAC3HDAC4HDAC1 | |
| SCHEMBL7606159 | 0.83 | LOXL2 (0.55) | ADRB2LOXL2TPH1ALDH1A1SLC6A3 | |
| SCHEMBL7606167 | 0.83 | LOXL2 (0.55) | ADRB2LOXL2TPH1ALDH1A1SLC6A3 | |
| SCHEMBL7120060 | 0.81 | ALDH1A1 (0.44) | ADRB2LOXL2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL7057465 | 0.80 | ADRB2 (0.46) | ADRB2LOXL2HDAC1HDAC6LTA4H | |
| Hydrochloric Acid SCHEMBL7120057 | 0.80 | ALDH1A1 (0.43) | ADRB2LOXL2HDAC1HDAC6ALDH1A1 | |
| SCHEMBL2291027 | 0.80 | LTA4H (0.51) | LOXL2LTA4HTPH1FFAR1PDPK1 | |
| SCHEMBL2291017 | 0.80 | LTA4H (0.51) | LOXL2LTA4HTPH1FFAR1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474405-A2 | PROCESS FOR THE PREPARATION OF 4-HETERO-SUBSTITUTED PHENYLALANINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068725-A2 | PROCESS FOR THE PREPARATION OF 4-HETERO-SUBSTITUTED PHENYLALANINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |