Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.53 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.53 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.53 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | TPH1 | P17752 | 6/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606159 | 1.00 | LOXL2 (0.55) | LOXL2GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL2291017 | 0.92 | LTA4H (0.51) | LOXL2GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL2291027 | 0.92 | LTA4H (0.51) | LOXL2GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL14210017 | 0.86 | LOXL2 (0.56) | LOXL2GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL6159998 | 0.83 | ADRB2 (0.50) | LOXL2TPH1PDPK1ADRB2FFAR1 | |
| SCHEMBL6575622 | 0.83 | ADRB2 (0.50) | LOXL2TPH1PDPK1ADRB2FFAR1 | |
| Hydrochloric Acid SCHEMBL6159994 | 0.82 | ADRB2 (0.49) | LOXL2TPH1PDPK1ADRB2FFAR1 | |
| Hydrochloric Acid SCHEMBL6575932 | 0.82 | ADRB2 (0.49) | LOXL2TPH1PDPK1ADRB2FFAR1 | |
| SCHEMBL17892219 | 0.81 | TPH1 (0.49) | LOXL2GRIK1GRIA1GRIA2GRIA3 | |
| SCHEMBL17892221 | 0.81 | TPH1 (0.49) | LOXL2GRIK1GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448408-B1 | CHEMICAL INTERMEDIATES IN PREPARATION OF N-MERCAPTOACYL DERIVATIVE OF PHENYLALANINE WITH PHARMALOGICAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2002-09-10 | — | — | US | disclosed |
| US-20020028946-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON GROUP S.P.A. (IT) | 2002-03-07 | — | — | US | disclosed |
| EP-0948492-B1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON SPA (IT) | 2001-07-11 | — | — | EP | disclosed |
| EP-0983217-A1 | METHOD FOR REMOVING HEAVY METALS FROM ORGANIC COMPOUNDS | ZAMBON GROUP S.p.A. (IT) | 2000-03-08 | — | — | EP | disclosed |
| EP-0948492-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON GROUP S.p.A. (IT) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998051647-A1 | METHOD FOR REMOVING HEAVY METALS FROM ORGANIC COMPOUNDS | ZAMBON GROUP S.P.A. (IT) | 1998-11-19 | — | — | WO | disclosed |
| WO-1998028284-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | ZAMBON GROUP S.P.A. (IT) | 1998-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028946-A1 | PROCESS FOR THE PREPARATION OF HETEROARYL-PHENYLALANINES | PAH, TYR, CYP2S1 | LOXL2 2239/4885GRIK1 1878/4885GRIA1 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.