Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 11/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 11/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6576372 | 0.91 | AKR1A1 (0.56) | AKR1A1AKR1B1GPR84 | |
| SCHEMBL6576328 | 0.89 | GPR84 (0.55) | AKR1A1AKR1B1GPR84HTR2ATRPM8 | |
| SCHEMBL6576362 | 0.87 | AKR1A1 (0.56) | AKR1A1AKR1B1HTR2APCSK9 | |
| SCHEMBL6576335 | 0.85 | AKR1A1 (0.53) | AKR1A1AKR1B1GPR84 | |
| SCHEMBL6575507 | 0.82 | AKR1A1 (0.55) | AKR1A1AKR1B1GPR84HTR2A | |
| SCHEMBL6577907 | 0.80 | AKR1A1 (0.56) | AKR1A1AKR1B1HTR2APCSK9 | |
| SCHEMBL6577852 | 0.79 | AKR1A1 (0.62) | AKR1A1AKR1B1TRPM8 | |
| SCHEMBL18383117 | 0.72 | GPR84 (1.00) | GPR84HTR2ATRPM8PCSK9 | |
| SCHEMBL445827 | 0.70 | AKR1A1 (1.00) | AKR1A1AKR1B1 | |
| SCHEMBL6629050 | 0.69 | AKR1A1 (0.44) | AKR1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135124-B1 | ANTIHYPERTRIGLYCERIDEMIC, ANTIHYPERGLYCEMIC, ANTI-ANGIOGENIC AND WOUND HEALING SUBSTITUDED INDOLEALKANOIC ACIDS | INST FOR PHARM DISCOVERY INC (US) | 2004-04-28 | — | — | EP | disclosed |