Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673788 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KMT2APARP10SIRT2ERN1 | |
| SCHEMBL6935704 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2APARP10SIRT2ERN1 | |
| SCHEMBL3682833 | 0.75 | KMT2A (0.53) | ALDH1A1KMT2APARP10ALDH1A3POLB | |
| SCHEMBL3688114 | 0.72 | XDH (0.40) | ALDH1A1KMT2APARP10HTTMEN1 | |
| SCHEMBL925957 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KMT2APARP10KDM4EGAA | |
| SCHEMBL16309558 | 0.71 | JUN (0.45) | ALDH1A1KMT2AERN1HTTMEN1 | |
| SCHEMBL12885255 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KMT2APARP10SIRT2ALDH1A3 | |
| SCHEMBL15548190 | 0.69 | ALOX15 (0.57) | ALDH1A1KMT2APARP10ALDH1A3POLB | |
| SCHEMBL6932787 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KMT2APARP10SIRT2ALDH1A3 | |
| SCHEMBL340676 | 0.69 | TSHR (0.43) | ALDH1A1KMT2APARP10HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313559-A4 | RECYCLABLE METATHESIS CATALYSTS | TRUSTEES BOSTON COLLEGE (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1313559-A2 | RECYCLABLE METATHESIS CATALYSTS | Trustees of Boston College (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002014376-A2 | RECYCLABLE METATHESIS CATALYSTS | TRUSTEES OF BOSTON COLLEGE (US) | 2002-02-21 | — | — | WO | disclosed |