Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ACLY | P53396 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137932 | 0.87 | ACLY (0.69) | ALDH1A1HPGDKDM4EHSD17B10ACLY | |
| SCHEMBL5279632 | 0.84 | ALDH1A1 (0.79) | ALDH1A1HPGDKDM4EHSD17B10ACLY | |
| SCHEMBL11123980 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL27919527 | 0.78 | KCNA5 (0.59) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL6566936 | 0.77 | CA1 (0.56) | ALDH1A1HPGDKDM4EHSD17B10ACLY | |
| SCHEMBL3555896 | 0.77 | ACLY (0.56) | ALDH1A1HPGDKDM4EHSD17B10ACLY | |
| SCHEMBL5798626 | 0.76 | KMT2A (0.45) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL14199550 | 0.76 | KCNA5 (0.50) | — | |
| SCHEMBL9850093 | 0.76 | KMT2A (0.60) | ALDH1A1HPGDKDM4EACLYKMT2A | |
| SCHEMBL7211680 | 0.75 | HPGD (0.73) | ALDH1A1HPGDHSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385820-A1 | ANTHRANILIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS ANTIARRHYTHMIA AGENTS, AND PHARMACEUTICAL PREPARATIONS THEREOF | Sanofi-Aventis Deutschland GmbH (DE) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002088073-A1 | ANTHRANILIC ACID AMIDES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AS ANTIARRHYTHMIA AGENTS, AND PHARMACEUTICAL PREPARATIONS THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-11-07 | — | — | WO | disclosed |
| US-5346904-A | BRONCHODILATOR AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-09-13 | — | — | US | disclosed |