Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583379 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL6585204 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL6585692 | 0.70 | MEN1 (0.37) | — | |
| SCHEMBL8326659 | 0.69 | KDM4E (0.45) | — | |
| SCHEMBL6586975 | 0.67 | UCHL1 (0.39) | — | |
| SCHEMBL29079914 | 0.67 | EPHX2 (0.36) | — | |
| SCHEMBL8300757 | 0.65 | LMNA (0.32) | — | |
| SCHEMBL6579377 | 0.64 | GABRA1 (0.32) | — | |
| SCHEMBL29079929 | 0.63 | ALDH1A1 (0.32) | — | |
| SCHEMBL1963460 | 0.61 | MTNR1A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944621-B1 | 2-IMIDAZOLINYLAMINOINDOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | PROCTER & GAMBLE (US) | 2004-09-01 | — | — | EP | disclosed |