Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182986 | 0.87 | MAOA (0.39) | CA2 | |
| SCHEMBL8172780 | 0.85 | GAA (0.47) | CYP3A4MEN1MAPTHPGDALOX15 | |
| SCHEMBL8175426 | 0.85 | SHBG (0.52) | CA2CYP3A4MEN1ALDH1A1MAPT | |
| SCHEMBL8188358 | 0.81 | ALDH1A1 (0.47) | CA2CYP3A4KDM4EMEN1CA12 | |
| SCHEMBL6583749 | 0.79 | PPARG (0.47) | CA2CYP3A4AKR1B1TNKS2ALDH1A1 | |
| SCHEMBL8183215 | 0.76 | CYP3A4 (0.53) | CYP3A4MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6584133 | 0.75 | TSHR (0.49) | CA2CYP3A4MEN1ALDH1A1ALOX15 | |
| SCHEMBL6583808 | 0.75 | TAAR1 (0.50) | CYP3A4ALDH1A1CYP2C9MAPK1CYP2C19 | |
| SCHEMBL8172479 | 0.75 | MAOA (0.65) | CA2MEN1ALDH1A1MAPTCYP2C9 | |
| SCHEMBL8173805 | 0.75 | IDO1 (0.43) | CA2CYP3A4KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |