Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962629 | 0.76 | SIGMAR1 (1.00) | SIGMAR1POLBCCR3 | |
| SCHEMBL6550825 | 0.76 | SIGMAR1 (1.00) | SIGMAR1POLBCCR3 | |
| SCHEMBL6587599 | 0.76 | KMT2A (0.60) | POLBALDH1A1KMT2A | |
| SCHEMBL4555805 | 0.75 | MAPT (0.48) | SIGMAR1KDM4EALDH1A1KMT2A | |
| SCHEMBL7718541 | 0.74 | SIGMAR1 (1.00) | SIGMAR1POLB | |
| SCHEMBL9373810 | 0.73 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL11801794 | 0.73 | CCR3 (0.89) | SIGMAR1CCR3KDM4EALDH1A1KMT2A | |
| SCHEMBL4555931 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2A | |
| SCHEMBL6589366 | 0.72 | HTR1A (0.61) | KMT2A | |
| Hydrochloric Acid SCHEMBL9311548 | 0.71 | POLB (0.60) | SIGMAR1POLBCCR3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | claimed |