Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.61 |
| ▸ | AKT1 | P31749 | 4/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588614 | 0.84 | HTR1A (0.66) | HTR1AOPRL1MEN1KMT2ADRD4 | |
| SCHEMBL6586359 | 0.83 | HTR1A (0.58) | HTR1AAKT1DRD4DRD3 | |
| Fumaric Acid SCHEMBL6592709 | 0.82 | HTR1A (0.58) | HTR1AAKT1AKT2AKT3 | |
| SCHEMBL6590854 | 0.76 | HTR1A (1.00) | HTR1ADRD4DRD3 | |
| SCHEMBL27489107 | 0.76 | HTR1A (1.00) | HTR1ADRD4DRD3 | |
| SCHEMBL6587938 | 0.74 | HTR1A (0.67) | HTR1AAKT1DRD4DRD3 | |
| SCHEMBL8443576 | 0.73 | ADRA1D (0.56) | HTR1A | |
| SCHEMBL6589346 | 0.73 | HTR1A (0.58) | HTR1AAKT1MEN1KMT2A | |
| SCHEMBL6586642 | 0.73 | HTR1A (0.55) | HTR1AAKT1MEN1KMT2AAKT2 | |
| SCHEMBL6586745 | 0.72 | HTR1A (0.48) | HTR1AMEN1KMT2ADRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | claimed |