Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584734 | 0.98 | HTR1A (0.41) | HTR1AHTR7MAOAMAOBMEN1 | |
| SCHEMBL6584980 | 0.91 | DRD2 (0.45) | HTR1AHTR7MEN1MAPTKMT2A | |
| SCHEMBL6586928 | 0.83 | MAOA (0.45) | HTR1AHTR7MAOAMAOBMEN1 | |
| SCHEMBL6584542 | 0.82 | DRD2 (0.56) | HTR1AHTR7MAOAMAOBDRD2 | |
| SCHEMBL6585521 | 0.82 | HTR1A (0.42) | HTR1AHTR7MAOAMAOBMEN1 | |
| SCHEMBL8310251 | 0.82 | DRD2 (0.46) | HTR1AHTR7MAOAMAOBMEN1 | |
| SCHEMBL6582486 | 0.82 | DRD2 (0.41) | HTR1AHTR7MAOAMAOBMEN1 | |
| SCHEMBL6583227 | 0.81 | HTR1A (0.44) | HTR1AHTR7MEN1MAPTKMT2A | |
| SCHEMBL8308852 | 0.81 | DRD2 (0.54) | HTR1AHTR7MAOAMAOBDRD2 | |
| SCHEMBL8310206 | 0.80 | HTR1A (0.42) | HTR1AHTR7MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |