Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787075 | 0.92 | MAPT (0.39) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| Acridan SCHEMBL6586926 | 0.90 | ALDH1A1 (0.32) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL8877458 | 0.79 | KDM4E (0.35) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL7797048 | 0.79 | HDAC4 (0.39) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL7587330 | 0.78 | BRD4 (0.33) | MAPTSMN1; SMN2GRK6TSHRNPC1 | |
| SCHEMBL7796571 | 0.76 | HDAC4 (0.46) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| Acridan SCHEMBL7594988 | 0.74 | HDAC3 (0.32) | HDAC4HDAC7HDAC5ALDH1A1TSHR | |
| SCHEMBL7793833 | 0.74 | HDAC4 (0.49) | HDAC4HDAC7HDAC5MAPTEGFR | |
| SCHEMBL7787061 | 0.73 | MAPT (0.37) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7797022 | 0.71 | HDAC4 (0.49) | HDAC4HDAC7HDAC5MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | claimed |
| CN-1156506-A | Chemiluminescent detection using 9, 10-acridan hydrolase | LUMIGEN CO LTD (US) | 1997-08-06 | — | — | CN | disclosed |