Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787061 | 0.88 | MAPT (0.37) | MAPTMEN1KMT2ACTSAALDH1A1 | |
| SCHEMBL7797026 | 0.79 | HDAC4 (0.38) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL8877458 | 0.79 | KDM4E (0.35) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL2452974 | 0.75 | GUCY1B2 (0.42) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL7796571 | 0.75 | HDAC4 (0.46) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL9394514 | 0.73 | HDAC4 (0.47) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL27488661 | 0.73 | HDAC4 (0.40) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL7787075 | 0.72 | MAPT (0.39) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| Acridan SCHEMBL6586926 | 0.72 | ALDH1A1 (0.32) | HDAC4HDAC7HDAC5MAPTMEN1 | |
| SCHEMBL7587330 | 0.71 | BRD4 (0.33) | MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | claimed |