Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080585 | 0.91 | ALDH1A1 (0.39) | ALOX15HNF4AGRM5KCNH2PDGFRB | |
| SCHEMBL6595262 | 0.81 | ALOX15 (0.51) | ALOX15GPR35PDE10AIGFBP3ALDH1A1 | |
| SCHEMBL6600048 | 0.81 | GPR35 (0.41) | ALOX15GPR35IGFBP3 | |
| SCHEMBL6080942 | 0.79 | HAO1 (0.39) | ALOX15GPR35HNF4AGRM5KCNH2 | |
| SCHEMBL6593629 | 0.78 | ALOX5 (0.49) | ALOX15GPR35PDE10AIGFBP3KDM4E | |
| SCHEMBL6593859 | 0.78 | GPR35 (0.56) | ALOX15GPR35IGFBP3ALDH1A1KDM4E | |
| SCHEMBL975858 | 0.78 | ALOX15 (0.56) | ALOX15GPR35PDE10AIGFBP3ALDH1A1 | |
| SCHEMBL6599593 | 0.78 | GPR35 (0.52) | ALOX15GPR35PDE10AIGFBP3ALDH1A1 | |
| SCHEMBL6594662 | 0.77 | GPR35 (0.51) | ALOX15GPR35PDE10AIGFBP3ALDH1A1 | |
| SCHEMBL6590987 | 0.77 | GPR35 (0.51) | ALOX15GPR35IGFBP3ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |