Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659961 | 0.86 | TDP1 (0.42) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL287525 | 0.79 | ALDH1A1 (0.50) | NPSR1ALDH1A1SMN1; SMN2TDP1MAPT | |
| SCHEMBL6227338 | 0.70 | NPSR1 (0.60) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL287312 | 0.70 | CHRNB2 (0.44) | KMT2AMEN1ALDH1A1TDP1HPGD | |
| Hydrochloric Acid SCHEMBL1194141 | 0.69 | NPSR1 (0.58) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7603207 | 0.68 | TDP1 (0.63) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10996044 | 0.67 | ALDH1A1 (0.63) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13100724 | 0.67 | HPGD (0.74) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12088129 | 0.67 | TDP1 (0.61) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28322559 | 0.66 | LMNA (0.62) | NPSR1KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | NPSR1 3243/4885KMT2A 4512/4885MEN1 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.